Lyophilization: An industry perspective on the application of modeling to lyophilization process scale up and transfer
While freeze-drying modeling is well established and documented, the extent of its application to routine operations, including development and manufacture, has not yet been fully realized. A survey, conducted by BioPhorum revealed that only a few companies use modeling for scale up and transfer. This paper outlines different applications of modeling to freeze-drying of biopharmaceutical products at commercial scale. It also signals the intent of BioPhorum to champion a wider adoption, and realize the full potential of modeling across the industry to standardize lyophilization practices, accelerate technology transfers and optimize operational performance

This deliverable has been published via the Americal Pharmaceutical Review website.
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