The biomanufacturing industry faces unprecedented challenges in meeting demand, reducing costs, and increasing manufacturing quality across current drug portfolios. In addition, new classes of biological medicines are being developed that require a radical shift in manufacturing processes. At the same time, industry must digitize and automate manufacturing processes and make full use of new manufacturing and digital technologies.
Key to this digitization of biomanufacturing plants is the role of manufacturing execution systems (MES). However, current MES solutions can be expensive, slow to implement, and lack the flexibility/agility/openness to be updated and supported efficiently. In addition, existing approaches are unsuitable for certain biomanufacturing scenarios, e.g., small-scale manufacturing plants and new biomanufacturing modalities.
Also, the biomanufacturing industry has not created a common view on future MES requirements to support the development of new products/services from vendors.
The purpose of the MES of the future manifesto is a call to action from the biomanufacturing industry to vendors of MES solutions. The manifesto articulates:
- The gap between the current generation of MES solutions and the needs of the biomanufacturing industry
- A realistic and achievable vision for the MES of the future that will meet the needs of the biomanufacturing plants of the future.
The manifesto is intended to stimulate collaboration between biomanufacturers and vendors of MES solutions that will outline roadmaps for future development.