This paper published in the PDA Journal describes a full scale, current Good Manufacturing Practices (cGMP) capable buffer stock blending system that has an open-source, configurable design and that overcomes the challenges of traditional buffer preparation.
Buffer Preparation
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Aug 2022 | Buffer Preparation, Buffer preparation open access docs, Deliverable, Deliverables Report, POI - Technology Strategy, Publication, Technology Strategy
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Functional Specification
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White paper addendum to the NIIMBL-BioPhorum buffer stock blending system – a more advanced concept for buffer manufacturing
Aug 2022 | Buffer Preparation, Deliverable, Deliverables Report, POI - Technology Strategy, Publication, Technology Strategy
This Addendum signals the release of the design and dataset from the performance testing of the NIIMBL BioPhorum buffer stock blending (BSB) system. It is being made available as ‘open source’, which the team hopes will encourage industry adoption of the BSB System. The paper provides the team’s evaluation of the testing outcomes. It also contains information relating to the methods and approach, and the lessons learned so that others can develop and improve this technology by understanding its benefits and applications.
BPI Europe May 2022 BSB presentation
May 2022 | Buffer Preparation, Deliverable, POI - Technology Strategy, Technology Strategy, Webinars and podcasts
NIIMBL-BioPhorum Buffer stock blending system: vision, collaboration, design and outcome On behalf of the NIIMBL-BioPhorum BSB System Team Presented by: Jeff Johnson – Biotech Design, LLC Biotechdesignllc.com BPI Europe – 18 May 2022